1912: The publication of William Christopher Handy's "Memphis Blues" changed the course of American popular song. Handy introduced an African-American folk tradition, the blues, into mainstream music. By the 1960s, the blues sound had significantly influenced the development of jazz and rock and roll, quintessential American musical forms. Born in Alabama in 1873, W. C. Handy attended Teachers Agricultural and Mechanical College in Huntsville. After a short stint teaching school, he began playing cornet with dance bands that traveled the Mississippi Delta. Handy transcribed and collected blues songs that he had heard on the road in the 1890s, but continued to play the ragtime dance tunes that audiences demanded. (Source: Library of Congress)